Saturday, March 21, 2009
Look at his loss, make it your gain
The author wrote "Kach knows it's only luck that spared his life, which makes him determined to use that life well. "This happened to me. I'll take one for the team, that's fine. But now I have to try and prevent others from having to go through what I and my family did. I lived for a reason. I shouldn't be here. I have to try to help other people."
John is now doing everything is his power to help promote the menigitis vaccine. It's so amazing that he's willing to take his trials and turn them to help others. He's already doing a lot of good things- meningitis vaccines are now required (or a waiver can be signed) for incoming college freshman in 24 states. For more information, click here
Could vaccines be a solution to cancer?
Check out this article! The University of Pittsburgh School of Medicine is working on a vaccine to prevent colon cancer. Wouldn't that be amazing if we could prevent this third leading cause of death? Scientists are making great strides with vaccines.
Vaccine To Prevent Colon Cancer Being Tested In Patients
ScienceDaily (Mar. 19, 2009) —
Researchers at the University of Pittsburgh School of Medicine have begun testing a vaccine that might be able to prevent colon cancer in people at high risk for developing the disease. If shown to be effective, it might spare patients the risk and inconvenience of repeated invasive surveillance tests, such as colonoscopy, that are now necessary to spot and remove precancerous polyps.
Colon cancer takes years to develop and typically starts with a polyp, which is a benign but abnormal growth in the intestinal lining, explained principal investigator Robert E. Schoen, M.D., M.P.H., professor of medicine and epidemiology at the University of Pittsburgh. Polyps that could become cancerous are called adenomas.
In a novel approach for cancer prevention, the Pitt vaccine is directed against an abnormal variant of a self-made cell protein called MUC1, which is altered and produced in excess in advanced adenomas and cancer. Vaccines currently in use to prevent cancer work via a different mechanism, specifically by blocking infection with viruses that are linked with cancer. For example, Gardasil protects against human papilloma virus associated with cervical cancer and hepatitis B vaccine protects against liver cancer.
"By stimulating an immune response against the MUC1 protein in these precancerous growths, we may be able to draw the immune system's fire to attack and destroy the abnormal cells," Dr. Schoen said. "That might not only prevent progression to cancer, but even polyp recurrence."
According to co-investigator Olivera Finn, Ph.D., professor and chair of the Department of Immunology at Pitt's School of Medicine, MUC1 vaccines have been tested for safety and immunogenicity in patients with late-stage colon cancer and pancreatic cancer.
"Patients were able to generate an immune response despite their cancer-weakened immune systems," she noted. "Patients with advanced adenomas are otherwise healthy and so they would be expected to generate a stronger immune response. That may be able to stop precancerous lesions from transforming into malignant tumors."
About a dozen people have received the experimental vaccine so far, and the researchers intend to enroll another 50 or so into the study. Participants must be between 40 and 70 years old and have a history of developing adenomas that are deemed advanced, meaning they are greater than or equal to 1 centimeter in size, are typed as villous or tubulovillous, or contain severely dysplastic, or abnormal, cells. After an initial dose of vaccine, the participants will get shots again two and 10 weeks later. Blood samples will be drawn to measure immune response at those time points as well as 12 weeks, 28 weeks and one year later.
People who develop advanced adenomas undergo regular surveillance with colonoscopy so that recurrent polyps, which are common, can be removed before matters get worse, Dr. Schoen said.
"Immunotherapy might be a good alternative to colonoscopy because it is noninvasive and nontoxic," he noted. "And, it could provide long-term protection."
Colorectal cancer is the third leading cause of cancer death in the United States. In 2008, the American Cancer Society estimated that there were more than 108,000 new cases of colon cancer, nearly 41,000 cases of rectal cancer, and almost 50,000 deaths due to both diseases.
Pitt's colon cancer vaccine is sponsored by the National Cancer Institute and The Nathan S. Arenson Fund for Pancreatic Cancer Research. Its adjuvant component, which enhances the immune system's ability to respond to the target protein, was developed and provided by Washington, D.C.-based Oncovir, Inc.
For More information about colon cancer, click here
Thursday, March 19, 2009
Are you up to date?
Here is the latest adult vaccine schedule straight from the Center for Disease Control. Check it out and see if you need to make a trip to the doctor be up to date. When we stay current in our vaccines, we can prevent some of the 50,000 deaths per year in adults(see video below)that are caused by vaccine preventable diseases. We all need to do our part!
Monday, March 16, 2009
Shots are for grown-ups, too
This video, from CNN, is a great reminder that vaccinations aren't just for children. We, as adults, need to remember to receive booster shots and still continue to track the vaccinations that have been done. Google had a new application called Google Health. With this program, you can easily track your vaccination records, along with all your medical records. Check it out and see what you think. All you need is a gmail account to use the application.
Autism anti-vaccination fears
I read this article OPINION: Kids Dying Because of Autism Anti-Vaccination Fears by Kevin Leitch. He talked about how the rate of individuals being vaccinated has decreased due to fears of autism. The population becomes vulnerable because of this. This article focused specifically on the increase in cases of whopping cough and the resulting deaths.
In the article, the author stated that, "How terribly sad and tragic that the same situation is playing out across so much of the affluent world – kids dying of vaccine preventable disease – because a few idiots think they know best and are willing to put the lives of others children at risk, when in the third world countries people are still dying by the tens of thousands from vaccine preventable disease and are desperate to get a hold of vaccines."
* I would like to know your thoughts on this issue. How can we make parents aware of the dangers of not being vaccinated, while at the same time dispelling myths?
*For more information, Here's a great article by the CDC.
Wednesday, February 25, 2009
Super Flu Vaccine
The video is about a possible future "super flu" vaccine that scientists are trying to develop. It's amazing at the strides that are being made and the possibilities for preventing all types of influenza, including H5N1- "avian flu."
source: cbsnews.com
Thursday, February 19, 2009
Frequently Asked Questions
As posted on kidshealth.org
What do immunizations do?
Vaccines work by preparing a child's body to fight illness. Each immunization contains either a dead or a weakened germ, or parts of it, that cause a particular disease.
The body practices fighting the disease by making antibodies that recognize specific parts of that germ. This permanent or longstanding response means that if someone is ever exposed to the actual disease, the antibodies are already in place and the body knows how to combat it and the person doesn't get sick. This is called immunity.
Will my child's immune system be weaker by relying on a vaccine?
No, the immune system makes antibodies against a germ, like the chickenpox virus, whether it encounters it naturally or is exposed to it through a vaccine.
Will the immunization give someone the very disease it's supposed to prevent?
This is one of the most common concerns about vaccines. However, it's impossible to get the disease from any vaccine made with dead (killed) bacteria or viruses or just part of the bacteria or virus.
Only those immunizations made from weakened (also called attenuated) live viruses — like the chickenpox (varicella) or measles-mumps-rubella (MMR) vaccine — could possibly make a child develop a mild form of the disease, but it's almost always much less severe than the illness that occurs when a person is infected with the disease-causing virus itself. However, for children with weakened immune systems, such as those being treated for cancer, these vaccines may cause problems.
The risk of disease from vaccination is extremely small. One live virus vaccine that's no longer used in the United States is the oral polio vaccine (OPV). The success of the polio vaccination program has made it possible to replace the live virus vaccine with a killed virus form known as the inactivated polio vaccine (IPV). This change has completely eliminated the possibility of polio disease being caused by immunization in the United States.
Why should I have my child immunized if all the other kids in school are immunized?
It is true that a single child's chance of catching a disease is low if everyone else is immunized. Yet if one person thinks about skipping vaccines, chances are that others are thinking the same thing. And each child who isn't immunized gives these highly contagious diseases one more chance to spread.
This actually happened between 1989 and 1991 when an epidemic of measles broke out in the United States. Lapsing rates of immunization among preschoolers led to a sharp increase in the number of measles cases, deaths, and children with permanent brain damage. Even in 2008, the number of cases of measles in the United States more than doubled from recent years. Most of the cases were among people who had not been vaccinated. Similar outbreaks of whooping cough (pertussis) struck Japan and the United Kingdom in the 1970s after immunization rates declined.
Although vaccination rates are fairly high in the United States, there's no reliable way of knowing if everyone your child comes into contact with has been vaccinated, particularly now that so many people travel to and from other countries. So, the best way to protect your child is through immunization.
Why should I subject my child to a painful shot if vaccines aren't 100% effective?
Few things in medicine work 100% of the time, but vaccines are one of the most effective weapons we have against disease — they work in 85% to 99% of cases. They greatly reduce your child's risk of serious illness (particularly when more and more people use them) and give diseases fewer chances to take hold in a population.
It can be difficult to watch kids get a shot, but the short-term pain is nothing compared with suffering through a potentially deadly bout of diphtheria, pertussis, or measles.
Why do kids who are healthy, active, and eating well need to be immunized?
Vaccinations are intended to help keep healthy kids healthy. Because vaccines work by protecting the body before disease strikes, if you wait until your child gets sick, it will be too late for the vaccine to work. The best time to immunize kids is when they're healthy.
Can immunizations cause a bad reaction in my child?
The most common reactions to vaccines are minor and include:
- redness and swelling where the shot was given
- fever
- soreness at the site where the shot was given
In rare cases, immunizations can trigger more serious problems, such as seizures or severe allergic reactions. If your child has a history of allergies to food or medication, or has had a problem with a vaccine previously, make sure to let the doctor know before any vaccines are given. Every year, millions of kids are safely vaccinated and almost all of them experience no significant side effects.
Meanwhile, research continually improves the safety of immunizations. The American Academy of Pediatrics (AAP) now advises doctors to use a diphtheria, tetanus, and pertussis vaccine that includes only specific parts of the pertussis cell instead of the entire killed cell. This vaccine, called DTaP, has been associated with even fewer side effects.
Why does my child need to be immunized if the disease has been eliminated?
Diseases that are rare or nonexistent in the United States, like measles and polio, still exist in other parts of the world. Doctors continue to vaccinate against them because it's easy to come into contact with illnesses through travel. That includes anyone who may not be properly immunized who's coming into the United States, as well as Americans traveling overseas.
If immunization rates fell, a disease introduced by someone visiting from another country could cause serious damage in an unprotected population. In 1994, polio was brought to Canada from India, but it didn't spread because so many people had been immunized. It's only safe to stop vaccinations for a particular disease when that disease has been eradicated worldwide, as in the case of smallpox.
How long does immunity last after getting a vaccine?
A few vaccines, like the two for measles or the series for hepatitis B, may make you immune for your entire life. Others, like tetanus, last for many years but require periodic shots (boosters) for continued protection against the disease.
The whooping cough (pertussis) vaccine also does not give lifelong immunity, and that may be one reason why there are still outbreaks of the disease. And although pertussis isn't a serious problem for older kids and adults, it can be for infants and young children. Because of this, adolescents and adults now receive a pertussis booster along with the tetanus and diphtheria booster (Tdap) — an important step in controlling this infection.
It's important to keep a record of vaccinations so the doctor knows when your child is due for a booster. Also make sure your child gets the flu vaccine each year, if it isn't in short supply. Having been immunized last year won't protect someone from getting the flu this year because the protection wears off and flu viruses constantly change. That's why the vaccine is updated each year to include the most current strains of the virus.
The flu vaccine reduces the average person's chances of catching the flu by up to 80% during the season. But because the flu vaccine doesn't prevent infection by all of the viruses that can cause flu-like symptoms, getting the vaccine isn't a guarantee that someone won't get sick during the season. But even if someone who's gotten the shot gets the flu, symptoms will usually be fewer and milder.
Are vaccines continuously studied and improved because they're unsafe?
The FDA's Center for Biologics Evaluation and Research is the government agency responsible for regulating vaccines in the United States. Working in conjunction with the CDC and the NIH, they continuously research and monitor vaccine safety and effectiveness.
New vaccines are licensed only after thorough laboratory studies and clinical trials, and safety monitoring continues even after a vaccine has been approved. There have been — and will continue to be — improvements (such as those that have already been made to the DTaP and polio vaccines, for example) that will minimize potential side effects and ensure the best possible safety standards.
Where can I find out more about immunizations?
The CDC's National Immunization Program maintains a website dedicated to helping consumers evaluate information about vaccinations from sources in the media and on the Internet.
And talk with your doctor about which immunizations your child needs — working together, you can help keep your child healthy.